Innovative pesticide-free head lice treatment introduced as millions of Canadian kids return to school Majority of parents surveyed surprised most current treatments pesticide- based; Canadian-studied Resultz(TM) highly effective, well-tolerated and uses established dermatologic ingredients OAKVILLE, ON, Sept. 6 /CNW/ - A new topical head lice treatment called Resultz(TM) is coming to Canadian pharmacies as the school year and prime head lice season begins, and offers Canadian parents a first - a pesticide-free head lice treatment that has not only been shown to be 96 per cent effective,(1) but is also colorless, odorless and fast-acting. One recent study in the United Kingdom reported nearly 40 per cent of children had head lice in a given year; extrapolated to Canadian population figures, more than 1.5 million Canadian primary school-aged children could face head lice this year.(2) Existing topical treatments approved for use in Canada contain pesticides as their active ingredients, including pyrethrin, permethrin 1% and lindane, all of which have potentially neurotoxic effects(3). One of these, lindane, was banned from future agricultural use by the Environmental Protection Agency in the United States just last month.(4) Unlike these agents, Resultz(TM) works in an entirely different way; it dissolves the wax that covers the exoskeleton of head lice, dehydrating lice and causing them to die. Resultz(TM) contains 50 per cent isopropyl myristate (active ingredient) and 50 per cent ST-cyclomethicone, ingredients commonly found in dermatologic preparations. A recent Decima Research survey(*) of more than 1,000 Canadian parents found that nearly 70 per cent of those surveyed were unaware that most medicated head lice treatments contained pesticides, and more than nine out of 10 indicated they would prefer to use a treatment that was pesticide-free if it were as effective or more effective than currently available products. Further, treatment failure was an issue; more than one-quarter of households surveyed who had experienced head lice reported that head lice re-appeared after it was thought to have been treated properly. "My personal experience with treating my own child when she had head lice ten years ago was frustrating, and, in talking to other parents, it seems like the situation today has not improved very much," says Ann Douglas, mother of four, author of 28 books on parenting and pregnancy and one of Canada's foremost parenting experts. "As a mom, I find it incredible that, while people have been making conscious choices to switch to pesticide-free lawn care, we are still expected to put small amounts of pesticides on our children's heads to treat their head lice. I know that parents are going to be very relieved to hear that there is now a pesticide-free treatment for head lice, and one that is clinically proven too." Head lice significant for parents, kids The recent Decima Research national survey(*) of more than 1,000 Canadian parents provides a glimpse into the significant impact of head lice. When asked about what impact did/does you/your child's head lice have on your day-to-day life: - More than 30 per cent cited having to stay away from friends and family. - 24 per cent cited a strong emotional impact on the child. - 23 per cent said missed days of work; of those, half missed two or more days and nearly one-quarter missed three or more days. "There is no question that head lice can impact anyone, and can be a disrupting force in a child's - and their family's - day-to-day life," says Toronto area elementary school principal L. Romano, who has seen first-hand the impact of head lice in schools. "Getting it treated and getting the child back into routine is the bottom line." The survey also found that there is strong awareness about the nature of head lice (94 per cent), but also confusion and lack of knowledge around head lice treatment options and their efficacy. Just 61 per cent of respondents indicated that head lice shampoos were considered very or completely effective and only 32 per cent indicated current medicated cream rinses were effective. The overwhelming majority indicated that natural or home remedies (mayonnaise, tea tree oil, petroleum jelly, cooking oil) were not considered effective, an assessment echoed by the Canadian Paediatric Society in its head lice position paper(3). "Head lice is common, and has a significant negative impact on children, parents and schools," says Denis Villeneuve, active member of the Canadian Pharmacists Association and the Quebec Order of Pharmacists. "Clearly, there is a need for a new approach like Resultz(TM) that can help parents get their children back to school quickly and with confidence." Canadian-led study evaluated Resultz(TM) A Winnipeg-based study(1) presented at the 2005 American Academy of Dermatology meeting in New Orleans evaluated Resultz(TM) for efficacy and safety. Twenty-nine of 30 subjects completed the study. Treatment was considered a success if two or fewer treatments over a 21-day period were required. The study showed 28 out of 29, or 96 per cent of the participants, were lice-free after using Resultz(TM). Four possible adverse events were reported during the trial, including scalp itch, irritation and erythema (redness). These adverse events were infrequent and mild. "The level of success we documented with Resultz(TM) in this trial in achieving well-tolerated lice-free status definitely exceeded expectations," says Winnipeg-based scientist Dr. Nalini Kaul. "We also took a look at the lice themselves, and found all were immobile at one minute post-treatment, and at the end of 24 hours, all were confirmed dead. As a head lice researcher, not to mention a mother, finding this kind of mortality and effectiveness using a pesticide-free product was exciting." Resistance has not been seen and is unlikely to develop with Resultz(TM) due to its unique dehydrating mode of action. Resistance means that, through genetic mutation, the lice have found a way to survive a treatment that was formerly effective. While formal studies to measure head lice resistance have not been performed in Canada, resistance to currently available pesticide-based treatments is an on-going global concern. Head lice resistance has been documented in countries as close as the United States, along with many other countries, including France, the United Kingdom, Czech Republic and Argentina.(3) In some areas, resistance to some current treatments is as high as 80 per cent.(5) More on Resultz(TM) Colorless and odorless, Resultz(TM) is easy to use. The first application takes 10 minutes (Day 1) and is repeated one week later (Day 7). After protecting the infested person's eyes with a towel, the product is applied to dry hair and scalp until the head and full length of hair are thoroughly saturated and wet to touch. Once this application is complete, the product stays on the hair for 10 minutes and is rinsed away with warm water. Distributed by ALTANA Pharma Inc. of Oakville, Ontario, Resultz(TM) can be purchased from pharmacies across Canada without a prescription in either 120 ml or 240 ml bottles. It is approved for use in persons aged four years and older.

CNW

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